Now showing items 1-11 of 11

    • Cerecetto, Hugo; González, M.; Risso, Mariela; Saenz, P.; Olea Azar, Claudio; Bruno, A. M.; Azqueta, Amaia; De Cerain, A. L.; Monge, A. (WILEY-V C H VERLAG GMBH, 2004-05)
      New 5-(2-arylethenyl)-1,2,4-triazine N-oxide and N,N'-dioxide derivatives were synthesized in order to obtain compounds as selective hypoxic cell cytotoxins. The desired products were obtained when the 5-methyl heterocycle ...
    • Pouteau, Y.; Motte, F.; Nony, T.; Galván Madrid, R.; Men’shchikov, A.; Bontemps, S.; Robitaille, J. F.; Louvet, Fabien; Ginsburg, A.; López Sepulcre, A.; Dell’Ova, P.; Gusdorf, A.; Sanhueza, P.; Stutz, Amelia Marie; Brouillet, N.; Thomasson, B.; Armante, M.; Baug, T.; Bonfand, M.; Busquet, G.; Csengeri, T.; Cunningham, N.; Fernández López, M.; Liu, H. L.; Olguin, F.; Towner, A. P. M.; Bally, J.; Braine, J.; Bronfman Aguiló, Leonardo Jaime; González, M.; Hennebelle, P.; Lu, X.; Menten, K. M.; Moraux, E.; Tatematsu, K.; Walker, D.; Whitworth, A. P. (EDP Sciences, 2021)
      Aims. The processes that determine the stellar initial mass function (IMF) and its origin are critical unsolved problems, with profound implications for many areas of astrophysics. The W43-MM2&MM3 mini-starburst ridge ...
    • Herrera, C.; Pinto Neira, J.; Fuentealba, D.; Sepúlveda C., José; Rosenkranz, Andreas; García Fierro, J. L.; González, M.; Escalona, N. (Wiley-VCH Verlag GMBH, 2021)
      Ni/CNTox catalysts with variable metal content have been prepared to investigate their emulsifying and catalytic properties for the liquid-phase conversion of furfural. The solid catalysts and emulsions were analyzed by ...
    • Rigol Olsen, Carolina; Olea Azar, Claudio; Mendizábal Emaldía, Fernando; Otero, Lucía; Gambino, Dinorah; González, M.; Cerecetto, Hugo (PERGAMON-ELSEVIER SCIENCE LTD, 2005-10)
      Cyclic voltammetry and electron spin resonance (ESR) techniques were used in the investigation of several potential antiprotozoal thiosemicarbazones nitrofurane derivatives. A self-protonation process involving the ...
    • Olea Azar, Claudio; Rigol Olsen, Carolina; Mendizábal Emaldía, Fernando; Briones, Rodolfo; Cerecetto, Hugo; Di Maio, R.; Risso, Mariela; González, M.; Porcal, Williams (PERGAMON-ELSEVIER SCIENCE LTD, 2003-01-01)
      The electron spin resonance (ESR) spectra of free radicals obtained by electrolytic or microsomal reduction of several potential antiprotozoal 1,2,5-oxadiazoles were characterized and analyzed. Ab initio molecular orbital ...
    • Olea Azar, Claudio; Rigol Olsen, Carolina; Opazo, L.; Morello Casté, Antonio; Maya Arango, Juan; Repetto Scaramelli, Yolanda; Aguirre, G.; Cerecetto, Hugo; Di Maio, R.; González, M.; Porcal, Williams (SOCIEDAD CHILENA DE QUIMICA, 2003-12)
      The Electron Spin Resonance (ESR) spectra of radicals obtained from two new potential antitrypanosomal drugs by Trypanosoma cruzi reduction were analyzed. DMPO Spin Trapping was used to investigate the possible formation ...
    • Olea Azar, Claudio; Rigol Olsen, Carolina; Mendizábal Emaldía, Fernando; Morello Casté, Antonio; Maya Arango, Juan; Moncada, C.; Cabrera, E.; Di Maio, R.; González, M.; Cerecetto, Hugo (TAYLOR & FRANCIS LTD, 2003-08)
      Electron spin resonance (ESR) spectra of radicals obtained from two analogues of the antiprotozoal drug nifurtimox by electrolytic and Trypanosoma cruzi reduction were analyzed. The electrochemistry of these compounds was ...
    • Aguirre, G.; Boiani, Lucía; Cerecetto, Hugo; Fernández, M.; González, M.; Denicola, Ana; Otero, L.; Gambino, Dinorah; Rigol Olsen, Carolina; Olea Azar, Claudio; Faúndez Cáceres, Mario Antonio (PERGAMON-ELSEVIER SCIENCE LTD, 2004-09-15)
      The in vitro growth inhibition activity of new thiosemicarbazone derivatives against the protozoan parasite Trypanosoma cruzi, the causative agent of American trypanosomiasis, are described. The designed compounds combine ...
    • Otero, Lucía; Maya Arango, Juan; Morello Casté, Antonio; Rigol, C.; Barriga, Germán; Rodríguez, J.; Folch, C.; Norambuena, Ester; González, M.; Olea Azar, Claudio; Cerecetto, Hugo; Gambino, Dinorah (Bentham Science Publishers Ltd., 2008)
      In order to get insight into the trypanocidal mechanism of action of a series of 5-nitrofuryl containing thiosemicarbazones some studies related to their bioreduction were performed. Electron spin resonance spectra of ...
    • Cerecetto, Hugo; González, M.; Lavaggi, M. L.; Aravena, M. A.; Rigol, C.; Olea Azar, Claudio; Azqueta, A.; López de Ceráin, Adela; Monge, A.; Bruno, A. M. (2006)
      The synthesis and evaluation as hypoxic selective cytotoxins of new derivatives of 2-amino or 2-hydroxyphenazine 5,10-dioxide are described. The compounds were developed as structural analogs of other bioreductive compounds ...
    • Rigol Olsen, Carolina; Olea Azar, Claudio; Mendizábal Emaldía, Fernando; Briones, Rodolfo; Cerecetto, Hugo; González, M. (ELSEVIER SCIENCE BV, 2006-09-29)
      Theoretical studies of molecular conformations and electronic properties calculations of eight 5-nitrofuryl thiosemicarbazone free radicals, by means of ab initio (R/UHF), and DFT (R/UB3LYP) methods are presented and ...